Myocardial ischaemia inhibits mitochondrial metabolism of 4-hydroxy-trans-2-nonenal
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چکیده
منابع مشابه
Myocardial ischaemia inhibits mitochondrial metabolism of 4-hydroxy-trans-2-nonenal.
Myocardial ischaemia is associated with the generation of lipid peroxidation products such as HNE (4-hydroxy-trans-2-nonenal); however, the processes that predispose the ischaemic heart to toxicity by HNE and related species are not well understood. In the present study, we examined HNE metabolism in isolated aerobic and ischaemic rat hearts. In aerobic hearts, the reagent [(3)H]HNE was glutath...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2008
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20081615